Gut health
Butyrate
Also called: sodium butyrate, tributyrin
A short-chain fat made by gut bacteria.
- Why people take it
- Gut lining, IBS.
- What the evidence says
- Little human evidence.
- How it is usually taken
- Usually 300 mg to 1 g a day of sodium or calcium butyrate.
- Be careful
- Unpleasant smell; generally safe.
- Medicines it can interact with
- No important medicine interactions are known, but tell your doctor and pharmacist about every supplement you take.
Other gut health
Common questions
What is Butyrate?
A short-chain fat made by gut bacteria.
Why do people take Butyrate?
Gut lining, IBS.
Does Butyrate work?
Little human evidence.
How much Butyrate do people take?
Usually 300 mg to 1 g a day of sodium or calcium butyrate.
Is Butyrate safe?
Unpleasant smell; generally safe.
Does Butyrate interact with medicines?
No important medicine interactions are known, but tell your doctor and pharmacist about every supplement you take.
Sources and further reading
Last reviewed 31 October 2026. Written by Satya Babu.
🔎 Search all supplements