Gut health

Serrapeptase

Also called: serratiopeptidase

An enzyme from silkworm bacteria.

Why people take it
Swelling, pain, sinusitis.
What the evidence says
Little good evidence.
How it is usually taken
Usually 10 to 60 mg a day on an empty stomach.
Be careful
May add to blood thinners.
Medicines it can interact with
May add to blood thinners.

Other gut health

Common questions

What is Serrapeptase?

An enzyme from silkworm bacteria.

Why do people take Serrapeptase?

Swelling, pain, sinusitis.

Does Serrapeptase work?

Little good evidence.

How much Serrapeptase do people take?

Usually 10 to 60 mg a day on an empty stomach.

Is Serrapeptase safe?

May add to blood thinners.

Does Serrapeptase interact with medicines?

May add to blood thinners.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

🔎 Search all supplements

For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.