Gut health

Digestive enzymes

Also called: pancreatin, bromelain, papain, lactase, alpha-galactosidase

Enzymes that help break down food.

Why people take it
Bloating, indigestion, lactose intolerance.
What the evidence says
Lactase helps lactose intolerance; alpha-galactosidase can reduce gas from beans. Little evidence for general bloating.
How it is usually taken
Usually with meals as directed on the product.
Be careful
Prescription pancreatic enzymes are needed for pancreas disease; see a doctor.
Medicines it can interact with
Antacids may reduce their effect; may affect acarbose.

Other gut health

Common questions

What is Digestive enzymes?

Enzymes that help break down food.

Why do people take Digestive enzymes?

Bloating, indigestion, lactose intolerance.

Does Digestive enzymes work?

Lactase helps lactose intolerance; alpha-galactosidase can reduce gas from beans. Little evidence for general bloating.

How much Digestive enzymes do people take?

Usually with meals as directed on the product.

Is Digestive enzymes safe?

Prescription pancreatic enzymes are needed for pancreas disease; see a doctor.

Does Digestive enzymes interact with medicines?

Antacids may reduce their effect; may affect acarbose.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.