Amino acids

L-arginine

Also called: arginine

An amino acid the body uses to make nitric oxide, which widens blood vessels.

Why people take it
Blood flow, blood pressure, erections, exercise.
What the evidence says
Small blood pressure drops; mixed results for exercise and erections.
How it is usually taken
Usually 3 to 6 g a day in divided doses.
Be careful
Can lower blood pressure too much with medicines. Not for people who recently had a heart attack, or with herpes.
Medicines it can interact with
Adds to blood-pressure lowering with BP medicines, nitrates and sildenafil or tadalafil. Avoid after a heart attack.

Other amino acids

Common questions

What is L-arginine?

An amino acid the body uses to make nitric oxide, which widens blood vessels.

Why do people take L-arginine?

Blood flow, blood pressure, erections, exercise.

Does L-arginine work?

Small blood pressure drops; mixed results for exercise and erections.

How much L-arginine do people take?

Usually 3 to 6 g a day in divided doses.

Is L-arginine safe?

Can lower blood pressure too much with medicines. Not for people who recently had a heart attack, or with herpes.

Does L-arginine interact with medicines?

Adds to blood-pressure lowering with BP medicines, nitrates and sildenafil or tadalafil. Avoid after a heart attack.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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