Other compounds

Methylene blue

Also called: methylthioninium

A dye and prescription medicine, sold online as a "brain" supplement.

Why people take it
Memory, energy.
What the evidence says
No good evidence as a supplement.
How it is usually taken
A prescription medicine, not a supplement; do not self-dose.
Be careful
Dangerous with antidepressants (serotonin syndrome). Use only as a medicine.
Medicines it can interact with
Serotonin syndrome with SSRIs, SNRIs and other antidepressants; dangerous with G6PD deficiency.

Other other compounds

Alpha-lipoic acidResveratrolQuercetinPterostilbeneNMNSpermidineFisetinPQQSulforaphaneDIMDHEAMelatoninCaffeine and L-theanineCannabidiol (CBD)Hemp seedBee pollenRoyal jellyPropolisManuka honeyChlorophyll

Common questions

What is Methylene blue?

A dye and prescription medicine, sold online as a "brain" supplement.

Why do people take Methylene blue?

Memory, energy.

Does Methylene blue work?

No good evidence as a supplement.

How much Methylene blue do people take?

A prescription medicine, not a supplement; do not self-dose.

Is Methylene blue safe?

Dangerous with antidepressants (serotonin syndrome). Use only as a medicine.

Does Methylene blue interact with medicines?

Serotonin syndrome with SSRIs, SNRIs and other antidepressants; dangerous with G6PD deficiency.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.